nwb-linkml/nwb_linkml/schema/core.nwb.icephys.yaml

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name: core.nwb.icephys
id: core.nwb.icephys
imports:
- core.nwb.base
- core.nwb.device
- hdmf-common.table
- nwb.language
default_prefix: core.nwb.icephys/
classes:
PatchClampSeries:
name: PatchClampSeries
description: An abstract base class for patch-clamp data - stimulus or response,
current or voltage.
is_a: TimeSeries
attributes:
name:
name: name
range: string
required: true
stimulus_description:
name: stimulus_description
description: Protocol/stimulus name for this patch-clamp dataset.
range: text
sweep_number:
name: sweep_number
description: Sweep number, allows to group different PatchClampSeries together.
range: uint32
data:
name: data
description: Recorded voltage or current.
multivalued: true
range: numeric
required: true
gain:
name: gain
description: Gain of the recording, in units Volt/Amp (v-clamp) or Volt/Volt
(c-clamp).
multivalued: false
range: float32
required: false
tree_root: true
CurrentClampSeries:
name: CurrentClampSeries
description: Voltage data from an intracellular current-clamp recording. A corresponding
CurrentClampStimulusSeries (stored separately as a stimulus) is used to store
the current injected.
is_a: PatchClampSeries
attributes:
name:
name: name
range: string
required: true
data:
name: data
description: Recorded voltage.
multivalued: false
range: CurrentClampSeries__data
required: true
bias_current:
name: bias_current
description: Bias current, in amps.
multivalued: false
range: float32
required: false
bridge_balance:
name: bridge_balance
description: Bridge balance, in ohms.
multivalued: false
range: float32
required: false
capacitance_compensation:
name: capacitance_compensation
description: Capacitance compensation, in farads.
multivalued: false
range: float32
required: false
tree_root: true
CurrentClampSeries__data:
name: CurrentClampSeries__data
description: Recorded voltage.
attributes:
name:
name: name
ifabsent: string(data)
range: string
required: true
equals_string: data
unit:
name: unit
description: Base unit of measurement for working with the data. which is
fixed to 'volts'. Actual stored values are not necessarily stored in these
units. To access the data in these units, multiply 'data' by 'conversion'
and add 'offset'.
range: text
value:
name: value
range: AnyType
required: true
IZeroClampSeries:
name: IZeroClampSeries
description: Voltage data from an intracellular recording when all current and
amplifier settings are off (i.e., CurrentClampSeries fields will be zero). There
is no CurrentClampStimulusSeries associated with an IZero series because the
amplifier is disconnected and no stimulus can reach the cell.
is_a: CurrentClampSeries
attributes:
name:
name: name
range: string
required: true
stimulus_description:
name: stimulus_description
description: An IZeroClampSeries has no stimulus, so this attribute is automatically
set to "N/A"
range: text
bias_current:
name: bias_current
description: Bias current, in amps, fixed to 0.0.
multivalued: false
range: float32
required: true
bridge_balance:
name: bridge_balance
description: Bridge balance, in ohms, fixed to 0.0.
multivalued: false
range: float32
required: true
capacitance_compensation:
name: capacitance_compensation
description: Capacitance compensation, in farads, fixed to 0.0.
multivalued: false
range: float32
required: true
tree_root: true
CurrentClampStimulusSeries:
name: CurrentClampStimulusSeries
description: Stimulus current applied during current clamp recording.
is_a: PatchClampSeries
attributes:
name:
name: name
range: string
required: true
data:
name: data
description: Stimulus current applied.
multivalued: false
range: CurrentClampStimulusSeries__data
required: true
tree_root: true
CurrentClampStimulusSeries__data:
name: CurrentClampStimulusSeries__data
description: Stimulus current applied.
attributes:
name:
name: name
ifabsent: string(data)
range: string
required: true
equals_string: data
unit:
name: unit
description: Base unit of measurement for working with the data. which is
fixed to 'amperes'. Actual stored values are not necessarily stored in these
units. To access the data in these units, multiply 'data' by 'conversion'
and add 'offset'.
range: text
value:
name: value
range: AnyType
required: true
VoltageClampSeries:
name: VoltageClampSeries
description: Current data from an intracellular voltage-clamp recording. A corresponding
VoltageClampStimulusSeries (stored separately as a stimulus) is used to store
the voltage injected.
is_a: PatchClampSeries
attributes:
name:
name: name
range: string
required: true
data:
name: data
description: Recorded current.
multivalued: false
range: VoltageClampSeries__data
required: true
capacitance_fast:
name: capacitance_fast
description: Fast capacitance, in farads.
multivalued: false
range: VoltageClampSeries__capacitance_fast
required: false
capacitance_slow:
name: capacitance_slow
description: Slow capacitance, in farads.
multivalued: false
range: VoltageClampSeries__capacitance_slow
required: false
resistance_comp_bandwidth:
name: resistance_comp_bandwidth
description: Resistance compensation bandwidth, in hertz.
multivalued: false
range: VoltageClampSeries__resistance_comp_bandwidth
required: false
resistance_comp_correction:
name: resistance_comp_correction
description: Resistance compensation correction, in percent.
multivalued: false
range: VoltageClampSeries__resistance_comp_correction
required: false
resistance_comp_prediction:
name: resistance_comp_prediction
description: Resistance compensation prediction, in percent.
multivalued: false
range: VoltageClampSeries__resistance_comp_prediction
required: false
whole_cell_capacitance_comp:
name: whole_cell_capacitance_comp
description: Whole cell capacitance compensation, in farads.
multivalued: false
range: VoltageClampSeries__whole_cell_capacitance_comp
required: false
whole_cell_series_resistance_comp:
name: whole_cell_series_resistance_comp
description: Whole cell series resistance compensation, in ohms.
multivalued: false
range: VoltageClampSeries__whole_cell_series_resistance_comp
required: false
tree_root: true
VoltageClampSeries__data:
name: VoltageClampSeries__data
description: Recorded current.
attributes:
name:
name: name
ifabsent: string(data)
range: string
required: true
equals_string: data
unit:
name: unit
description: Base unit of measurement for working with the data. which is
fixed to 'amperes'. Actual stored values are not necessarily stored in these
units. To access the data in these units, multiply 'data' by 'conversion'
and add 'offset'.
range: text
value:
name: value
range: AnyType
required: true
VoltageClampSeries__capacitance_fast:
name: VoltageClampSeries__capacitance_fast
description: Fast capacitance, in farads.
attributes:
name:
name: name
ifabsent: string(capacitance_fast)
range: string
required: true
equals_string: capacitance_fast
unit:
name: unit
description: Unit of measurement for capacitance_fast, which is fixed to 'farads'.
range: text
value:
name: value
range: float32
required: true
VoltageClampSeries__capacitance_slow:
name: VoltageClampSeries__capacitance_slow
description: Slow capacitance, in farads.
attributes:
name:
name: name
ifabsent: string(capacitance_slow)
range: string
required: true
equals_string: capacitance_slow
unit:
name: unit
description: Unit of measurement for capacitance_fast, which is fixed to 'farads'.
range: text
value:
name: value
range: float32
required: true
VoltageClampSeries__resistance_comp_bandwidth:
name: VoltageClampSeries__resistance_comp_bandwidth
description: Resistance compensation bandwidth, in hertz.
attributes:
name:
name: name
ifabsent: string(resistance_comp_bandwidth)
range: string
required: true
equals_string: resistance_comp_bandwidth
unit:
name: unit
description: Unit of measurement for resistance_comp_bandwidth, which is fixed
to 'hertz'.
range: text
value:
name: value
range: float32
required: true
VoltageClampSeries__resistance_comp_correction:
name: VoltageClampSeries__resistance_comp_correction
description: Resistance compensation correction, in percent.
attributes:
name:
name: name
ifabsent: string(resistance_comp_correction)
range: string
required: true
equals_string: resistance_comp_correction
unit:
name: unit
description: Unit of measurement for resistance_comp_correction, which is
fixed to 'percent'.
range: text
value:
name: value
range: float32
required: true
VoltageClampSeries__resistance_comp_prediction:
name: VoltageClampSeries__resistance_comp_prediction
description: Resistance compensation prediction, in percent.
attributes:
name:
name: name
ifabsent: string(resistance_comp_prediction)
range: string
required: true
equals_string: resistance_comp_prediction
unit:
name: unit
description: Unit of measurement for resistance_comp_prediction, which is
fixed to 'percent'.
range: text
value:
name: value
range: float32
required: true
VoltageClampSeries__whole_cell_capacitance_comp:
name: VoltageClampSeries__whole_cell_capacitance_comp
description: Whole cell capacitance compensation, in farads.
attributes:
name:
name: name
ifabsent: string(whole_cell_capacitance_comp)
range: string
required: true
equals_string: whole_cell_capacitance_comp
unit:
name: unit
description: Unit of measurement for whole_cell_capacitance_comp, which is
fixed to 'farads'.
range: text
value:
name: value
range: float32
required: true
VoltageClampSeries__whole_cell_series_resistance_comp:
name: VoltageClampSeries__whole_cell_series_resistance_comp
description: Whole cell series resistance compensation, in ohms.
attributes:
name:
name: name
ifabsent: string(whole_cell_series_resistance_comp)
range: string
required: true
equals_string: whole_cell_series_resistance_comp
unit:
name: unit
description: Unit of measurement for whole_cell_series_resistance_comp, which
is fixed to 'ohms'.
range: text
value:
name: value
range: float32
required: true
VoltageClampStimulusSeries:
name: VoltageClampStimulusSeries
description: Stimulus voltage applied during a voltage clamp recording.
is_a: PatchClampSeries
attributes:
name:
name: name
range: string
required: true
data:
name: data
description: Stimulus voltage applied.
multivalued: false
range: VoltageClampStimulusSeries__data
required: true
tree_root: true
VoltageClampStimulusSeries__data:
name: VoltageClampStimulusSeries__data
description: Stimulus voltage applied.
attributes:
name:
name: name
ifabsent: string(data)
range: string
required: true
equals_string: data
unit:
name: unit
description: Base unit of measurement for working with the data. which is
fixed to 'volts'. Actual stored values are not necessarily stored in these
units. To access the data in these units, multiply 'data' by 'conversion'
and add 'offset'.
range: text
value:
name: value
range: AnyType
required: true
IntracellularElectrode:
name: IntracellularElectrode
description: An intracellular electrode and its metadata.
is_a: NWBContainer
attributes:
name:
name: name
range: string
required: true
cell_id:
name: cell_id
description: unique ID of the cell
multivalued: false
range: text
required: false
description:
name: description
description: Description of electrode (e.g., whole-cell, sharp, etc.).
multivalued: false
range: text
required: true
filtering:
name: filtering
description: Electrode specific filtering.
multivalued: false
range: text
required: false
initial_access_resistance:
name: initial_access_resistance
description: Initial access resistance.
multivalued: false
range: text
required: false
location:
name: location
description: Location of the electrode. Specify the area, layer, comments
on estimation of area/layer, stereotaxic coordinates if in vivo, etc. Use
standard atlas names for anatomical regions when possible.
multivalued: false
range: text
required: false
resistance:
name: resistance
description: Electrode resistance, in ohms.
multivalued: false
range: text
required: false
seal:
name: seal
description: Information about seal used for recording.
multivalued: false
range: text
required: false
slice:
name: slice
description: Information about slice used for recording.
multivalued: false
range: text
required: false
tree_root: true
SweepTable:
name: SweepTable
description: '[DEPRECATED] Table used to group different PatchClampSeries. SweepTable
is being replaced by IntracellularRecordingsTable and SimultaneousRecordingsTable
tables. Additional SequentialRecordingsTable, RepetitionsTable, and ExperimentalConditions
tables provide enhanced support for experiment metadata.'
is_a: DynamicTable
attributes:
name:
name: name
range: string
required: true
sweep_number:
name: sweep_number
description: Sweep number of the PatchClampSeries in that row.
multivalued: true
range: uint32
series:
name: series
description: The PatchClampSeries with the sweep number in that row.
multivalued: true
range: PatchClampSeries
series_index:
name: series_index
description: Index for series.
multivalued: false
range: SweepTable__series_index
required: true
tree_root: true
SweepTable__series_index:
name: SweepTable__series_index
description: Index for series.
is_a: VectorIndex
attributes:
name:
name: name
ifabsent: string(series_index)
range: string
required: true
equals_string: series_index
IntracellularElectrodesTable:
name: IntracellularElectrodesTable
description: Table for storing intracellular electrode related metadata.
is_a: DynamicTable
attributes:
name:
name: name
range: string
required: true
description:
name: description
description: Description of what is in this dynamic table.
range: text
electrode:
name: electrode
description: Column for storing the reference to the intracellular electrode.
multivalued: true
range: IntracellularElectrode
tree_root: true
IntracellularStimuliTable:
name: IntracellularStimuliTable
description: Table for storing intracellular stimulus related metadata.
is_a: DynamicTable
attributes:
name:
name: name
range: string
required: true
description:
name: description
description: Description of what is in this dynamic table.
range: text
stimulus:
name: stimulus
description: Column storing the reference to the recorded stimulus for the
recording (rows).
multivalued: false
range: IntracellularStimuliTable__stimulus
required: true
tree_root: true
IntracellularStimuliTable__stimulus:
name: IntracellularStimuliTable__stimulus
description: Column storing the reference to the recorded stimulus for the recording
(rows).
is_a: TimeSeriesReferenceVectorData
attributes:
name:
name: name
ifabsent: string(stimulus)
range: string
required: true
equals_string: stimulus
IntracellularResponsesTable:
name: IntracellularResponsesTable
description: Table for storing intracellular response related metadata.
is_a: DynamicTable
attributes:
name:
name: name
range: string
required: true
description:
name: description
description: Description of what is in this dynamic table.
range: text
response:
name: response
description: Column storing the reference to the recorded response for the
recording (rows)
multivalued: false
range: IntracellularResponsesTable__response
required: true
tree_root: true
IntracellularResponsesTable__response:
name: IntracellularResponsesTable__response
description: Column storing the reference to the recorded response for the recording
(rows)
is_a: TimeSeriesReferenceVectorData
attributes:
name:
name: name
ifabsent: string(response)
range: string
required: true
equals_string: response
IntracellularRecordingsTable:
name: IntracellularRecordingsTable
description: A table to group together a stimulus and response from a single electrode
and a single simultaneous recording. Each row in the table represents a single
recording consisting typically of a stimulus and a corresponding response. In
some cases, however, only a stimulus or a response is recorded as part of an
experiment. In this case, both the stimulus and response will point to the same
TimeSeries while the idx_start and count of the invalid column will be set to
-1, thus, indicating that no values have been recorded for the stimulus or response,
respectively. Note, a recording MUST contain at least a stimulus or a response.
Typically the stimulus and response are PatchClampSeries. However, the use of
AD/DA channels that are not associated to an electrode is also common in intracellular
electrophysiology, in which case other TimeSeries may be used.
is_a: AlignedDynamicTable
attributes:
name:
name: name
ifabsent: string(intracellular_recordings)
range: string
required: true
equals_string: intracellular_recordings
description:
name: description
description: Description of the contents of this table. Inherited from AlignedDynamicTable
and overwritten here to fix the value of the attribute.
range: text
electrodes:
name: electrodes
description: Table for storing intracellular electrode related metadata.
multivalued: false
range: IntracellularElectrodesTable
required: true
stimuli:
name: stimuli
description: Table for storing intracellular stimulus related metadata.
multivalued: false
range: IntracellularStimuliTable
required: true
responses:
name: responses
description: Table for storing intracellular response related metadata.
multivalued: false
range: IntracellularResponsesTable
required: true
tree_root: true
SimultaneousRecordingsTable:
name: SimultaneousRecordingsTable
description: A table for grouping different intracellular recordings from the
IntracellularRecordingsTable table together that were recorded simultaneously
from different electrodes.
is_a: DynamicTable
attributes:
name:
name: name
ifabsent: string(simultaneous_recordings)
range: string
required: true
equals_string: simultaneous_recordings
recordings:
name: recordings
description: A reference to one or more rows in the IntracellularRecordingsTable
table.
multivalued: false
range: SimultaneousRecordingsTable__recordings
required: true
recordings_index:
name: recordings_index
description: Index dataset for the recordings column.
multivalued: false
range: SimultaneousRecordingsTable__recordings_index
required: true
tree_root: true
SimultaneousRecordingsTable__recordings:
name: SimultaneousRecordingsTable__recordings
description: A reference to one or more rows in the IntracellularRecordingsTable
table.
is_a: DynamicTableRegion
attributes:
name:
name: name
ifabsent: string(recordings)
range: string
required: true
equals_string: recordings
table:
name: table
description: Reference to the IntracellularRecordingsTable table that this
table region applies to. This specializes the attribute inherited from DynamicTableRegion
to fix the type of table that can be referenced here.
range: IntracellularRecordingsTable
SimultaneousRecordingsTable__recordings_index:
name: SimultaneousRecordingsTable__recordings_index
description: Index dataset for the recordings column.
is_a: VectorIndex
attributes:
name:
name: name
ifabsent: string(recordings_index)
range: string
required: true
equals_string: recordings_index
SequentialRecordingsTable:
name: SequentialRecordingsTable
description: A table for grouping different sequential recordings from the SimultaneousRecordingsTable
table together. This is typically used to group together sequential recordings
where a sequence of stimuli of the same type with varying parameters have been
presented in a sequence.
is_a: DynamicTable
attributes:
name:
name: name
ifabsent: string(sequential_recordings)
range: string
required: true
equals_string: sequential_recordings
simultaneous_recordings:
name: simultaneous_recordings
description: A reference to one or more rows in the SimultaneousRecordingsTable
table.
multivalued: false
range: SequentialRecordingsTable__simultaneous_recordings
required: true
simultaneous_recordings_index:
name: simultaneous_recordings_index
description: Index dataset for the simultaneous_recordings column.
multivalued: false
range: SequentialRecordingsTable__simultaneous_recordings_index
required: true
stimulus_type:
name: stimulus_type
description: The type of stimulus used for the sequential recording.
multivalued: true
range: text
tree_root: true
SequentialRecordingsTable__simultaneous_recordings:
name: SequentialRecordingsTable__simultaneous_recordings
description: A reference to one or more rows in the SimultaneousRecordingsTable
table.
is_a: DynamicTableRegion
attributes:
name:
name: name
ifabsent: string(simultaneous_recordings)
range: string
required: true
equals_string: simultaneous_recordings
table:
name: table
description: Reference to the SimultaneousRecordingsTable table that this
table region applies to. This specializes the attribute inherited from DynamicTableRegion
to fix the type of table that can be referenced here.
range: SimultaneousRecordingsTable
SequentialRecordingsTable__simultaneous_recordings_index:
name: SequentialRecordingsTable__simultaneous_recordings_index
description: Index dataset for the simultaneous_recordings column.
is_a: VectorIndex
attributes:
name:
name: name
ifabsent: string(simultaneous_recordings_index)
range: string
required: true
equals_string: simultaneous_recordings_index
RepetitionsTable:
name: RepetitionsTable
description: A table for grouping different sequential intracellular recordings
together. With each SequentialRecording typically representing a particular
type of stimulus, the RepetitionsTable table is typically used to group sets
of stimuli applied in sequence.
is_a: DynamicTable
attributes:
name:
name: name
ifabsent: string(repetitions)
range: string
required: true
equals_string: repetitions
sequential_recordings:
name: sequential_recordings
description: A reference to one or more rows in the SequentialRecordingsTable
table.
multivalued: false
range: RepetitionsTable__sequential_recordings
required: true
sequential_recordings_index:
name: sequential_recordings_index
description: Index dataset for the sequential_recordings column.
multivalued: false
range: RepetitionsTable__sequential_recordings_index
required: true
tree_root: true
RepetitionsTable__sequential_recordings:
name: RepetitionsTable__sequential_recordings
description: A reference to one or more rows in the SequentialRecordingsTable
table.
is_a: DynamicTableRegion
attributes:
name:
name: name
ifabsent: string(sequential_recordings)
range: string
required: true
equals_string: sequential_recordings
table:
name: table
description: Reference to the SequentialRecordingsTable table that this table
region applies to. This specializes the attribute inherited from DynamicTableRegion
to fix the type of table that can be referenced here.
range: SequentialRecordingsTable
RepetitionsTable__sequential_recordings_index:
name: RepetitionsTable__sequential_recordings_index
description: Index dataset for the sequential_recordings column.
is_a: VectorIndex
attributes:
name:
name: name
ifabsent: string(sequential_recordings_index)
range: string
required: true
equals_string: sequential_recordings_index
ExperimentalConditionsTable:
name: ExperimentalConditionsTable
description: A table for grouping different intracellular recording repetitions
together that belong to the same experimental condition.
is_a: DynamicTable
attributes:
name:
name: name
ifabsent: string(experimental_conditions)
range: string
required: true
equals_string: experimental_conditions
repetitions:
name: repetitions
description: A reference to one or more rows in the RepetitionsTable table.
multivalued: false
range: ExperimentalConditionsTable__repetitions
required: true
repetitions_index:
name: repetitions_index
description: Index dataset for the repetitions column.
multivalued: false
range: ExperimentalConditionsTable__repetitions_index
required: true
tree_root: true
ExperimentalConditionsTable__repetitions:
name: ExperimentalConditionsTable__repetitions
description: A reference to one or more rows in the RepetitionsTable table.
is_a: DynamicTableRegion
attributes:
name:
name: name
ifabsent: string(repetitions)
range: string
required: true
equals_string: repetitions
table:
name: table
description: Reference to the RepetitionsTable table that this table region
applies to. This specializes the attribute inherited from DynamicTableRegion
to fix the type of table that can be referenced here.
range: RepetitionsTable
ExperimentalConditionsTable__repetitions_index:
name: ExperimentalConditionsTable__repetitions_index
description: Index dataset for the repetitions column.
is_a: VectorIndex
attributes:
name:
name: name
ifabsent: string(repetitions_index)
range: string
required: true
equals_string: repetitions_index